Mohammad Kawsar Sharif Siam

Sharif joined Department of Pharmacy, BracU University as a Senior Lecturer. Before joining Brac University, he worked as a Lecturer at the Department of Pharmacy, East West University Bangladesh. He completed his Bachelor of Pharmacy (BPharm) from North South University and his MSc in Pharmacogenetics and Stratified Medicine at the Department of Genetics, University College London (UCL), UK. His previous research works included cell line drug sensitivity prediction in pharmacogenomic dataset. He developed various animal models of Liver, Kidney and Eye diseases during his undergraduate and postgraduate studies.

In his lifelong journey in biology, genetics and technology, he acquired expertise in application of databases, machine learning algorithms, data mining, and become familiar with scientific computing tools such as Python, R-RStudio, MySQL, PubChem, CHEMAXON, Cytoscape, KNIME, WEKA, SIDER.

He is an active member of International Society for Computational Biology (ISCB), Royal Society of Chemistry (RSC), UK.

School of Pharmacy

Address

Level: 5
Kha-224 Merul Badda
Dhaka 1212. Bangladesh

Ext. 2519
[email protected]

Scopus Author Profile

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Education
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- 2011 - 2012 Masters of Science in Pharmacogenetics and Stratified Medicine, University College London (UCL), London, UK. (World Ranking-4th Position)
- 2006-2010 Bachelor of Pharmacy, North South University, Dhaka, Bangladesh.
- 2003-2005 Higher Secondary School Certificate (HSC), Notre Dame College (Science Group 1), Dhaka, Dhaka Board.
- 1993-2003 Secondary School Certificates (SSC), Government Laboratory High School, Dhaka, Dhaka Board.
Publications
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Selected Publications

Journals

Albakova, Z., Siam, M. K. S., Sacitharan, P. K., Ziganshin, R. H., Ryazantsev, D. Y., & Sapozhnikov, A. M. (2021). Extracellular heat shock proteins and cancer: New perspectives. Translational Oncology, 14(2). https://doi.org/10.1016/j.tranon.2020.100995

Kabir, E. R., Mustafa, N., Nausheen, N., Siam, M. K. S., & Syed, E. U. (2021). Exploring existing drugs: proposing potential compounds in the treatment of COVID-19. Heliyon, 7(2). https://doi.org/10.1016/j.heliyon.2021.e06284

Chowdhury, U. F., Sharif Shohan, M. U., Hoque, K. I., Beg, M. A., Siam, M. K. S., & Moni, M. A. (2021). A computational approach to design potential siRNA molecules as a prospective tool for silencing nucleocapsid phosphoprotein and surface glycoprotein gene of SARS-CoV-2. Genomics, 113(1), 331–343. https://doi.org/10.1016/j.ygeno.2020.12.021

Siam, M. K. S., Sarker, A., & Sayeem, M. M. S. (2020). In silico drug design and molecular docking studies targeting Akt1 (RAC-alpha serine/threonine-protein kinase) and Akt2 (RAC-beta serine/threonine-protein kinase) proteins and investigation of CYP (cytochrome P450) inhibitors against MAOB (monoamine oxida. Journal of Biomolecular Structure and Dynamics. https://doi.org/10.1080/07391102.2020.1802335

Rajib, S. A., & Siam, M. K. S. (2020). Characterization and analysis of mammalian AKR7A gene promoters: Implications for transcriptional regulation. Biochemical Genetics, 58(1), 171–188. https://doi.org/10.1007/s10528-019-09936-y

Siam, M. K. S., Khan, A., & Khan, T. M. (2013). Medical and pharmacy students’ knowledge and perceptions about generic medicines in Bangladesh. Journal of Pharmaceutical Health Services Research, 4(1), 57–61. https://doi.org/10.1111/jphs.12008

Rahman, R., Rashid, S. M. M., Sayeem, M., Sharif, I., & Siam, M. K. S. (2011). Surface proteins, potential drug target for antiviral therapy against Nipah virus and in silico drug design. Clinical Biochemistry, 44(13, Supplement), 34. https://doi.org/https://doi.org/10.1016/j.clinbiochem.2011.08.1035

Siam, M. K. S., Hossain, M., Farooq, A. O., Islam, M. A., Uddin, M. E., & Sharif, M. (2011). Studies on the anti-inflammatory and analgesic efficacy of saraca asoca in laboratory animals. Archives of Pharmacy Practice, 2(1), 16–21. Retrieved from https://archivepp.com/en/issue/archiveapp-vol2-iss1

Imtiaz, M. F., Siam, M. K. S., Das, M., Lopa, S. D., Farooq, A. O., Sharif, M. M., & Awal, M. A. (2010). Arsenic (As) contamination in different food and dietary samples from several districts of Bangladesh and Arsenic (As) detection, mitigation and toxicity measurement and impact of dietary arsenic exposure on human health. Archives of Pharmacy Practice, 1(1), 20–24. Retrieved from https://archivepp.com/en/issue/archiveapp-vol1-iss1

Conferences

Siam, M. K. S., Sayeem, M. M. S., Mohammed, M. K., & Rajib, M. S. A. (2012). In-silico experiment of the human CFTR sequence to identify common disease causing mutation and development of small drug therapies for cystic fibrosis. In 20th Annual Conference of Intelligent Systems in Molecular Biology. California, USA.

Conferences, Talks, and Speaking Engagements

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2016 2015	- International conference on Intelligent Systems for Molecular Biology (ISMB); Orlando, Florida, USA. - 1) Big Data in Medicine: Exemplars and Opportunities in Data Science; Cambridge Big Data, Cambridge, UK on June 2015. - 2) Cambridge Cheminformatics Meeting, Centre for Molecular Sciences and Informatics, Department of Chemistry, University of Cambridge.
2014	- 1) Autumn 2014 UK QSAR meeting, Cambridge Crystallographic Data Centre (CCDC), University of Cambridge on September 2014. - 2) Young Modellers' Forum, SOAS, London on November 2014. (Poster Presenter) - 3) Cambridge Cheminformatics Meeting , EBI, Hinxton, UK on November 2014 - 4) Cambridge Cheminformatics Network Meeting, Centre for Molecular Sciences and Informatics, Department of Chemistry, University of Cambridge on February 2014.
2013	- UCC Symposium, Unilever Lecture Theatre, Unilever Centre for Molecular Sciences and Informatics, Department of Chemistry, University of Cambridge on October 2013 (Oral presentation)
2012	- 1) International Pharmaceutical Federation (FIP) Centennial Congress in Amsterdam, Netherland on October 2012 (Poster Presenter) - 2) The Science of Stratified Medicine, University of Liverpool, United Kingdom July 2012. - 3) The World Health Assembly of World Health Organization (WHO), United Nations, Geneva, Switzerland on May 2012 (Invited Speaker)
2011	- International Pharmaceutical Federation (FIP) World Congress in Hyderabad, India on September 2011. (Invited Speaker)
2010	- 23rd Federation of Asian Pharmaceutical Association Congress (FAPA) in Taipei, Taiwan on November, 2010 (Invited Speaker) -

Awards, Honors

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2016 2015 2014	Recipient of University Council ALF Award 2016, University of Cambridge, UK 1) Departmental development award- Dept. of Chemistry, University of Cambridge, UK 2) Awarded Darwin College Santander grant for contributing in advancing the science- Darwin college, University of Cambridge, UK Awarded Certificate of Postgraduate Studies (CPGS)- University of Cambridge, UK
2013	Prestigious Unilever-Cambridge Studentship for studying PhD at University of Cambridge, UK.
2011	UCL Genetics Institute (UGI) Scholarships for studying MSc in Pharmacogenetics and Stratified Medicine-UCL, UK.
2011	Research Grant of $4,500 from International Pharmaceutical Federation (FIP) Challenge on TB section for designing a project on Tuberculosis Intervention in Bangladesh.
2010	Young Investigator Award sponsorship for ISOMRM 2010 in Zhunan, Taiwan.
2009	Summer Research Fellowship, College of Pharmacy; University of Michigan; MI, USA.
2008	IPSF World Congress DF Event Grant, Cluj-Napoca, Romania.

Membership

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2015-current

2012-current

1) Affiliate Member, Royal Society of Chemistry (RSC), UK

2) Member and Ambassador, European Association for Cancer Research (EACR), UK.

1) Member, International Society for Computational Biology (ISCB),

2) UCL Computational Life and Medical Sciences Network.

2011-current

Member, International Pharmaceutical Federation (FIP) - the global pharmacy professional network.

Research Areas/Interests
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- Pharmacogenetics
- Chemoinformatics
- Drug repurposing
- Machine Learning
- AI
- Pharmacy